The Neuropathology of Alcohol-specific Brain Damage, or Does Alcohol Damage the Brain?
نویسندگان
چکیده
منابع مشابه
The neuropathology of alcohol-related brain damage.
Excessive alcohol use can cause structural and functional abnormalities of the brain and this has significant health, social and economic implications for most countries in the world. Even heavy social drinkers who have no specific neurological or hepatic problems show signs of regional brain damage and cognitive dysfunction. Changes are more severe and other brain regions are damaged in patien...
متن کاملDoes a "moderate" alcohol intake damage the brain?
A range of volumetric and neurochemical analyses were carried out on the brains of 14 "moderate" drinkers. These data were compared with previous studies from controls and alcoholics. Volumetric measurements consistently suggest a loss of cerebral tissue although the differences were not statistically significant. Changes in the lipid and water content of the white matter were noted and the sig...
متن کاملMolecular genetics of alcohol-related brain damage.
AIMS In the scientific literature it has been repeatedly hypothesized that there is a heritable susceptibility to thiamine deficiency comparable to other hereditary metabolic disorders. The aim of this paper is to review the most recent knowledge on the genetic susceptibility to the development of alcohol-related Wernicke-Korsakoff syndrome (WKS). METHODS A literature review was carried out l...
متن کاملSpecial issue on alcohol and brain damage.
When the brain is damaged by alcohol, whether in early development or in later life, the distress caused is often prolonged because the damage may be permanent or very slow to recover, but the condition is not fatal as with some other complications of excessive consumption of alcohol. The finding in an Irish acute general hospital, that 25% of ‘delayed discharge’ was accounted for by patients w...
متن کاملAlcohol-Related Brain Damage in Humans
Chronic excessive alcohol intoxications evoke cumulative damage to tissues and organs. We examined prefrontal cortex (Brodmann's area (BA) 9) from 20 human alcoholics and 20 age, gender, and postmortem delay matched control subjects. H & E staining and light microscopy of prefrontal cortex tissue revealed a reduction in the levels of cytoskeleton surrounding the nuclei of cortical and subcortic...
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ژورنال
عنوان ژورنال: Journal of Neuropathology and Experimental Neurology
سال: 1998
ISSN: 0022-3069
DOI: 10.1097/00005072-199802000-00001